Menactra (MenACYW-DT)
Quadrivalent meningococcal diphtheria toxoid conjugate vaccine · Sanofi Pasteur
Prevents
Dosing schedules
2-dose schedule for children aged 9–23 months
For: Infants (0–1 year)
| Dose | Age | Minimum interval from previous dose |
|---|---|---|
| Dose 1 (Menactra) | 9 months | – |
| Dose 2 (Menactra) | 12 months (earliest 12 months) | 90 days |
Approved by the Drug Administration of Vietnam on 03/10/2018
Source: Prevention of meningococcal disease in Vietnam (Science and Technics Publishing House, 2024; Vietnam Association of Preventive Medicine). Reviewed on 05/10/2026.
Single-dose schedule for people aged 24 months to 55 years
| Dose | Age | Minimum interval from previous dose |
|---|---|---|
| Single dose (Menactra) | One 0.5 ml dose | – |
One dose. People aged 15 to 55 who remain at risk of meningococcal disease can receive 1 booster at least 4 years after the previous dose.
Source: Recommended vaccination schedules for all ages in Vietnam (2026 edition). Reviewed on 07/10/2026.
Special precautions
Indicated from 9 months to 55 years of age.
Giving with other vaccines
- Prevenar 13 (PCV13): should not be given on the same day; if given on different days, allow at least 28 days between them. In people with asplenia, splenic dysfunction or HIV infection: do NOT give Menactra (MenACWY-D) and PCV13 at the same time, because this reduces the antibody response to 3 pneumococcal serotypes (4, 6B, 18C). Give PCV13 first and Menactra 4 weeks later.
- Tetraxim: can be given on the same day. In children aged 4–6 years, giving Menactra after a vaccine containing a full dose of diphtheria toxoid (Daptacel/DTaP) markedly reduces the meningococcal antibody response. Give them at the same time, or give Menactra first.
- Bexsero (4CMenB): can be given on the same day. Bexsero and Menactra can be given at the same visit at two different anatomical sites without affecting safety or immunogenicity.
- Gardasil 9: can be given on the same day. HPV vaccine (Gardasil 9) and quadrivalent meningococcal vaccine (Menactra) can be given at the same time to adolescents at two different sites, to make the most of each visit and reduce travel costs.
Pregnancy and breastfeeding
Safe