Prevents

Dosing schedules

3+1 schedule (2, 3, 4 months, booster in the second year)

For: Infants (0–1 year)

Dose	Age	Minimum interval from previous dose
Dose 1 (6-in-1)	2 months (earliest 6 weeks)	–
Dose 2 (6-in-1)	3 months (earliest 10 weeks)	28 days
Dose 3 (6-in-1)	4 months (earliest 14 weeks)	28 days
Dose 4, booster (6-in-1) Booster	16 months (earliest 12 months)	180 days

For infants from 6 weeks of age. Three primary doses at least 4 weeks apart (or two doses at least 8 weeks apart).

Source: Recommended vaccination schedules for all ages in Vietnam (2026 edition). Reviewed on 07/10/2026.

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Special precautions

Indicated for children from 6 weeks of age. Intramuscular injection in the anterolateral thigh.

Contraindications and deferrals

Contraindication Grade III or higher anaphylaxis after a previous dose · Component: Any component of the vaccine
Absolute contraindication to further doses containing the same components.
Contraindication Encephalopathy of unknown cause within 7 days after a pertussis-containing vaccine · Component: Pertussis component
Switch to DT vaccine (diphtheria and tetanus only, without the pertussis component).
Defer High fever ≥ 38.0°C or acute illness
Postpone vaccination until the child has been fever-free for at least 3 days and is well.

Reactions after vaccination and what to do

Mild fever below 38.5°C, mild pain and swelling at the injection site Common

Onset: Within 24–48 hours after vaccination · Lasts: 1–2 days

Home care: Give the child plenty of fluids or breastfeed more often, and dress the child in light clothing. If the fever is ≥ 38.5°C, give paracetamol 10–15 mg/kg body weight every 4–6 hours. Do not put anything on the injection site.

Go to a health facility immediately if: High fever above 39°C that does not come down, seizures, noisy or wheezy breathing, blue lips or fingertips, or continuous high-pitched crying for more than 3 hours.

Pregnancy and breastfeeding

For children under 24 months